Urine Alkalinisation by Citrates Improves Pain and Other Symptoms in Patients with Interstitial Cystitis/bladder Pain Syndrome. Assessment of Urine Ph Using Compact Ph Meters at Every Voiding

Hypothesis / aims of study Acidic urine may play a role in the development of symptoms in patients with interstitial cystitis/bladder pain syndrome (IC/BPS) because activation of afferent C-fibres can be triggered by excessive H + ions in acidic urine. In a previous study, which was presented at the AUA in 2009, we demonstrated that urine alkalinisation could be effective for reducing symptoms, especially pain at voiding and sleep disturbance, in patients with IC/BPS. Here, we report the result of the subsequent study that was designed to evaluate the precise data of urine pH value and pain intensity. A compact pH meter was used to measure the pH and the intensity of pain was recorded at every voiding. We also investigated sleep disturbance in this study.